Is Trazodone (Desyrel) Safe for Cats?
Why it’s a problem
Trazodone is used in cats by some veterinarians, but cat doses are extremely small and the margin is narrow. Cats exposed to human tablets have been reported to show deep sedation, paradoxical panic, or serotonin syndrome with fever and tremors. A single human tablet may represent many cat doses.
How to keep your pet safe
Store trazodone where a cat cannot paw a bottle off a shelf or counter. If your cat stresses during travel or clinic visits, ask your veterinarian for cat-appropriate sedation advice rather than sharing pills.
Warning signs to watch for
Profound drowsiness, wobbliness, dilated pupils, vomiting, drooling; paradoxical agitation or vocalizing; serotonin toxicity: tremors, rapid breathing, fast heart rate, fever, seizures.
When to call the vet
Call your veterinarian or a pet poison hotline promptly with the tablet strength and the number possibly eaten. Do not give anything else at home and do not wait for symptoms in a small cat.
Common questions
My cat licked a trazodone tablet — is that a problem?
Possibly — cat doses are tiny, so even partial ingestion matters. Call your vet or a pet poison hotline for guidance based on your cat’s weight and the amount involved.
Is trazodone ever used for cats?
Yes, some veterinarians prescribe it at very small doses for travel or exam stress, but only under veterinary direction. Never share your own tablets.
More medications hazards for cats
This page is general educational information, not a substitute for professional veterinary advice. Every pet is different — if your animal ate or touched something concerning, contact your veterinarian or a pet poison hotline right away. In the US: Pet Poison Helpline (855) 764-7661, ASPCA Animal Poison Control (888) 426-4435 (fees may apply).