All hazards › Medications › Pregabalin (Lyrica) & cats

Is Pregabalin (Lyrica) Safe for Cats?

☠️ Toxic
✅ Cross-checked against veterinary poison-control guidance · Oct 2026 audit
⚠️ Educational info only. If your pet just ate or touched something and looks unwell, skip the reading and call your vet — or Pet Poison Helpline (US): (855) 764-7661, ASPCA Poison Control (US): (888) 426-4435.
No. Pregabalin can cause profound sedation and neurological effects in cats — any ingestion needs an immediate call to your vet.

Why it’s a problem

Pregabalin is potent at very small milligram amounts, so a human capsule can massively overdose a cat. Reported effects in cats include deep sedation, wobbliness, and tremors, and severe exposures can depress breathing. Although some vets use it for feline pain, human products and home dosing are unsafe.

How to keep your pet safe

Store pregabalin out of any cat’s reach — a single capsule loose on the floor is enough to matter. Pain management for cats should come only from a veterinary prescription.

Warning signs to watch for

Severe drowsiness, wobbliness, falling over, tremors, drooling, vomiting, slow breathing; severe cases: collapse, low body temperature.

When to call the vet

Contact your veterinarian or a pet poison hotline immediately. Cats that become heavily sedated may need monitoring until the drug clears.

Common questions

My cat swallowed a Lyrica capsule — will she die?

A single capsule can cause dangerous sedation in a cat, and larger amounts are riskier. Call your vet or a pet poison hotline right away rather than waiting for symptoms.

Do vets ever use pregabalin for cats?

Occasionally, at strictly calculated doses. That does not make human capsules safe to share — never self-dose a pet with any prescription drug.

More medications hazards for cats

This page is general educational information, not a substitute for professional veterinary advice. Every pet is different — if your animal ate or touched something concerning, contact your veterinarian or a pet poison hotline right away. In the US: Pet Poison Helpline (855) 764-7661, ASPCA Animal Poison Control (888) 426-4435 (fees may apply).