All hazards › Medications › Omeprazole (Prilosec) & cats

Is Omeprazole (Prilosec) Safe for Cats?

⚠️ Only With Vet OK
✅ Cross-checked against veterinary poison-control guidance · Oct 2026 audit
⚠️ Educational info only. If your pet just ate or touched something and looks unwell, skip the reading and call your vet — or Pet Poison Helpline (US): (855) 764-7661, ASPCA Poison Control (US): (888) 426-4435.
A single Prilosec tablet is unlikely to harm a cat, but omeprazole for a cat should only ever come from your vet.

Why it’s conditional

Omeprazole is low in acute toxicity, so a cat that swallows one tablet often shows no signs beyond possible mild GI upset. Vets do use it in cats for specific conditions, but unsupervised use can mask kidney disease or other problems that vomiting may be signaling. A cat that eats many tablets risks more obvious GI upset.

How to keep your pet safe

Keep Prilosec stored away from cats and never self-dose. Vomiting in cats can be the first sign of serious disease, so diagnosis should come before any acid reducer.

Warning signs to watch for

Usually mild: drooling, vomiting, diarrhea, or food refusal; larger ingestions can cause lethargy and more persistent GI upset.

When to call the vet

Call your veterinarian or a pet poison hotline if more than one tablet was eaten. Any ongoing vomiting or appetite loss in a cat needs an exam regardless of cause.

Common questions

My cat swallowed one of my Prilosec tablets — is that OK?

One tablet is unlikely to cause more than mild upset in a healthy adult cat. A call to your vet or a poison hotline is still worthwhile, especially for a kitten or a cat with kidney disease.

My cat vomits often — can I just give omeprazole?

No. Frequent vomiting in cats can signal kidney, thyroid, or GI disease that needs diagnosis. Masking it with an acid reducer can delay treatment that matters.

My cat chewed into my Prilosec bottle — what should I do?

Estimate how many tablets are missing and call your vet or a pet poison hotline. A large ingestion can cause real GI upset even though the drug itself is mild.

More medications hazards for cats

This page is general educational information, not a substitute for professional veterinary advice. Every pet is different — if your animal ate or touched something concerning, contact your veterinarian or a pet poison hotline right away. In the US: Pet Poison Helpline (855) 764-7661, ASPCA Animal Poison Control (888) 426-4435 (fees may apply).