Is Alprazolam (Xanax) Safe for Cats?
Why it’s a problem
Cats lack several liver pathways needed to clear benzodiazepines efficiently, so effects can be stronger and longer lasting than expected. Alprazolam may cause deep sedation with slow breathing, or paradoxically, agitation and aggression. Oral benzodiazepines have also been linked to sudden liver failure in cats in reported cases.
How to keep your pet safe
Keep alprazolam stored in a drawer or cabinet — a pill left on the counter is an easy target for a curious cat. If your cat is anxious, a veterinarian can recommend safer, cat-specific approaches.
Warning signs to watch for
Profound lethargy, wobbliness, drooling, vomiting, slow breathing, low temperature; paradoxical signs: hyperactivity, aggression, dilated pupils, vocalizing; severe cases: collapse, yellow gums from liver injury.
When to call the vet
Call your veterinarian or a pet poison hotline at once — do not wait for symptoms. Bloodwork may be needed to check the liver after benzodiazepine exposure in cats.
Common questions
My cat ate one of my anxiety pills — is it an emergency?
Yes — benzodiazepines can sedate cats deeply and have been linked to liver failure. Call your vet or a poison hotline immediately, even if your cat seems normal.
Is it OK to dose my cat with my anti-anxiety med before a vet trip?
No. Never self-dose a pet. Ask your veterinarian about cat-appropriate options for travel and clinic anxiety.
More medications hazards for cats
This page is general educational information, not a substitute for professional veterinary advice. Every pet is different — if your animal ate or touched something concerning, contact your veterinarian or a pet poison hotline right away. In the US: Pet Poison Helpline (855) 764-7661, ASPCA Animal Poison Control (888) 426-4435 (fees may apply).